Medical devices extracorporeal oxygenators

Extracorporeal medical machines (e.g., artificial kidney, pump-oxygenator) perfused with blood have been an effective part of the therapeutic armamentarium for many years. These devices all rely on systemic heparinization to provide blood compatibility. Despite continuous efforts to improve anticoagulation techniques, many patients still develop coagulation abnormalities with the use of these devices (1-3). Even longer perfusion times may occur with machines such as the membrane oxygenator. In such cases, the drawbacks of systemic heparinization are multiplied (4). A number of ap-... [Pg.484]

Housings for extracorporeal devices (acrylics, poly(carbonates), poly(methylpentane)], catheters, angioplasty balloons, sutures, vascular grafts (polyester textiles, expanded PTFE), medical tubing oxygenator and hemdi-alysis membranes... [Pg.330]

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