Mathematical Modeling of an Immobilized Backed Reactor

Understanding mass transfer restrictions is important in evaluating the kinetic properties of the immobilized enzyme to achieve efficient bioreactor design. To develop 

Based on these assnmptions, the following steady-state diffusion-reaction equations for mass balances of substrate concentrations within an immobilized enzyme can be written as 

For simplification, similar dimensionless parameters to those shown in Equation 4.57 are usually introduced, and Equation 4.65 can be rewritten in a normalized form with dimensionless parameters as in Equation 4.68  

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