Maternal chromosome

Nasmyth I think Tim Hunt s question is a sensible one. Normally p57 is expressed on the maternal chromosome and not on the paternal one, because according to this hypothesis the father s chromosome does not express it because he doesn t want to slow down growth. If this is the case, then if you had an extra copy and introduced it on a bacterial artificial chromosome (BAC) into the maternal genome, what would happen to growth This is a crucial prediction of the hypothesis. 

Kubiak Recognition of paternal and maternal chromosomes was a nice explanation for the prolongation of the first mitosis in the mouse, but... 

This disorder appears to involve paternal imprinting of UBE3A, encoding a ubiquitin-protein ligase so that this gene product must be produced from the maternal chromosome. 

Allelic exclusion is the process by which a cell uses either the gene from the maternal chromosome or the allelic gene from the paternal chromosome, but not both. Allelic exclusion occurs in genes encoding antibodies and T cell receptors. 

Genetic traits are passed from one generation to the next. When a sperm fertilizes an ovum, a conceptus is created from a single set of maternal chromosomes and a single set of paternal chromosomes. As this fertilized egg divides, each daughter cell will receive one copy of each of these chromosomes. The genes on... 

In conclusion, during meiosis, the paternal and maternal chromosomes are briefly paired to be separated again during the first meiotic division. Any failure of pairing or separation leads to an abnormal distribution of chromosomes in the gamete. 

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