Mass spectrometry cerebrosides

From the sea anemone M. senile was isolated j3-glucopyranosyl-( 1 - l)-ceramide, the structure of which was determined by mass spectrometry, H-n.m.r. spectroscopy, and chemical splitting. The major sphingosine in the cerebroside is a new base containing two double bonds and branching at one double bond, namely, 2-amino-D-eryf/jro-l,3-dihydroxy-9-methyl-( , E)-octadeca-4,8-diene. The major fatty acids are Ci6 0 and C20 o a-hydroxy acids.133... 

S. B. Levery, M. S. Toledo, R. L. Doong, A. H. Straus, and H. K. Takahashi, Comparative analysis of ceramide structural modification found in fungal cerebrosides by electrospray tandem mass spectrometry with low energy collision-induced dissociation of Li + adduct ions, Rapid Commun. Mass Spectrom., 14 (2000) 551-563. 

Cha, S.W. et al., Colloidal graphite-assisted laser desorption/ionization mass spectrometry and MS" of small molecules. 1. Imaging of cerebrosides directly from rat brain tissue, Anal. Chem., 79, 2373, 2007. 

A cerebroside was isolated from S. commune and purified by HPLC. Its structure was elucidated by mainly chemical methods of degradation followed by nuclear magnetic resonance and mass spectrometry of the different constituents (78). 

Cation radicals in mass spectrometry, 526 Cellobiose, 991-992 Cellulose, 994 Cembrene, 1027 Center of symmetry, 264—265 in meso-2,3-butanediol, 280 Cephalexin, 803 Cephalosporins, 803 Cerebrosides, 1047 Chair conformation... 

Sawabe, A., Morita, M., Okamoto, T. and Ouchi, S. (1994) The location of double bonds in a cerebroside from edible fungi (mushroom) estimated by B/E linked scan fast atom bombardment mass spectrometry. Biol Mass Spectrom., 23, 660-4. 

Separation and Identification of Cerebrosides in Cerebrospinal Fluid by Gas Chromatography-Mass Spectrometry... 

Komori et al. (555) reported the isolation of a cerebroside mixture (987) and two nucleosides, thymine desoxyribonucleoside (988) and uracil desoxyribonucleoside (989), from Acanthaster planci. Structure elucidation was based on and C-NMR spectrometry as well as on El- and FD mass spectrometry. Similar cerebroside mixtures which showed nearly identical IR-spectra could be extracted from Luidia qui naria and Astropecten latespinosus. The mycosporine-like amino acids (990-994) have been obtained from alcoholic extracts of the starfish Asterina pectinifera 656). 

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