Malpighian epidermis

Schleim-saure /. mucic acid, -schicht /. layer of sHme or mucilage or mucus specif., mucous layer, Malpighian layer (of the epidermis). -stoff m. sHmy substance mucin. 

Transport of vitamin D3 away from the dermal junction of skin is accomplished by a 52 kDa serum vitamin D-binding protein (DBP). Serum DBP is a member of the a-fetoprotein-albumin super family [36], DBP has high affinity for vitamin D3, but does not bind to its precursors or the products of previtamin D3 side-reactions, lumisterol and tachysterol [37], Accumulation of 7-dehydrocholesterol in skin occurs in sebaceous glands at the malpighian layer of the epidermis, mostly in the stratum spinosum and stratum basal... 

In 1968, Paul Langerhans discovered the presence of a particular type of epidermal cell in humans, which is now named after him. The Langerhans cell (LC) is a mobile dendritic cell that has no desmosomes and is found in most multilayered malpighian epithelia. LCs make up 2-5% of epidermal cells. They come from the medulla and migrate towards and within the skin and stay within the epidermis for 2 weeks at the most. 

Malpighian layer (stratum germina-tivum) The iimermost layer of the epidermis of mammalian skin, separated from the underlying dermis by a fibrous basement membrane. It is only in this layer of the epidermis that active cell division ( mitosis) occurs. As the cells produced by these divisions age and mature, they migrate upwards through the layers of the epidermis to replace the cells being continuously worn away at the surface. 

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