Maize foramsulfuron

Introduced in 2001 and subsequently commercialized by Bayer CropScience, the three-way mixture of foramsulfuron with iodosulfuron-methyl-sodium and isoxadifen-ethyl is used for postemergent weed control in maize. Foramsulfuron,... 

Brankov M., Dragicevic V., Simic M., Spasojevic I. Dynamics of soluble protein content and grain yield in maize inbred lines influenced by foramsulfuron. Conference Proceedings Fifth International Scientific Agricultural Symposium "Agrosym 2014" October 23-26, Jahorina, Republic of Srpska, Bosnia, 2014, p. 497-450. 

Foramsulfuron (AE FI30360) [48] is a postemergence sulfonylurea herbicide for the control of major grass species and certain broadleaf weeds in maize (Table 2.2.21). It is applied with the safener isoxadifen-ethyl (AE F122006) (Fig. 2.2.7) and in some products in combination with small quantities iodosulfuron-methyl-sodium [49]. 

The basis of selectivity of foramsulfuron in the presence of the safener isoxadifen-ethyl is a more rapid rate of metabolic detoxification in maize compared with target weeds, in which little or no degradation of the parent sulfonylurea occurs [51]. Three main routes of metabolism have been established in maize - a hydrolytic cleavage of the sulfonylurea bridge, a deformylation of the amino group and oxidative metabolism of the dimethoxypyrimidine ring. 

This compound was recently developed as a safener for the sulfonylurea herbicide foramsulfuron in maize. Metabolism studies revealed that isoxadifen-ethyl also acts by enhancement of foramsulfuron metabolism in maize, while it does not influence the rate of metabolism of this herbicide in susceptible weed species [17, 18]. 

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