Magnolia mutabilis

Isol. from the leaves of Magnolia mutabilis and from the bark of X. tingoassuiba. Formed by heating (—)-Asarinin with EtOH/HCl. Mp 122-124 . [a]> -68 (c, 0.5 in CHCI3). 

Magnolia campbelli and M. mutabilis Doryphora sassafras Endlicher ... 

Staphylococcus aureus, Mycobacterium smegmatis, and Candida albicans. Davis also stated that (-)anonaine (39) can employ a hypotensive effect in mice and rabbits and was shown to be an inhibitor of dopaminergic response. Also, the toxicity of anonaine HCl was demonstrated in mice at 200 rng kg. A related compound, liriodenine (40), had similar antibacterial activity to anonaine. Liriodenine exhibited fairly potent cytotoxic and cytopathic effects against Herpes simplex virus type 1 (HSV-1) [64], Furthermore, the methylenedioxy functionality of this molecule is beleived to be involved in the observed activity [64], Liriodenine has been isolated from the stem bark of several Magnolia spp. such as M. campbelii, M. mutabilis [24] and the trunk bark of M watsonii and M. obovata [57],... 

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See also in sourсe #XX -- [ , , ]

See also in sourсe #XX -- [ , ]

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