Magnetic biosensor

In this chapter, the role of electrochemical and magnetic biosensors towards development of portable, compact and inexpensive biochip devices has been demonstrated. Direct measurement of electrochemical signals, such as ferrocene molecule, is a preferred approach to simplify the process towards miniaturized biochip devices. Furthermore, the use of magnetic probes promises to increase the sensitivity. Future research may be in the direction of developing new probes, e.g. nanomaterials for differing bio-applications. 

Chemla YR, Grossman HL, Poon Y et al (2000) Ultrasensitive magnetic biosensor for homogeneous immunoassay. Proc Natl Acad Sci USA 97 14268-14272... 

More details on inductance and other magnetically based sensors can be found in Chapter 3, Magnetic Biosensors. 

Meyer M.H.F., Stehr M., BhujuS., Krause H.J., Hartmann M., Miethe R, Singh M., and Keusgen M. 2007b. Magnetic biosensor for the detection of Yersinia pestis. Journal of Microbiological Methods 68 218-224. 

There is an increasing need for higher sensitivity and specificity of detection for biosensors. Magnetic particles, by the use of the magnetoresistive (MR) effect, have been developed as labels for biosensing. These magnetic biosensors have... 

MEMS-Based Magnetic Biosensors Introduction Most MEMS-based magnetic biosensors manipulate a magnetic bead where... 

Meyer MHF et al (2007) CRP determination based on a novel magnetic biosensor. Biosens Bioelectron 22(6) 973-979... 

Chemla, Y.R. Grossman, H.L. Poon, Y. McDermott, R. Stevens, R. Alper, M.D. Clarke, J. (2000), Ultrasensitive magnetic biosensor for homogenous assay. Proc. Natl Acad. Sci, 97 14268-14272. 

H. Wang, Y. Chen, A. Hassibi, A. Scherer, A. Hajimiri, A frequency-shift CMOS magnetic biosensor array with single-bead sensitivity and no external magnet, in Sohd-State Circuits Conference-Digest of Technical Papers, 2009. ISSCC 2009. IEEE International, 2009, pp. 438-439. 

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