Madasiatic acids

N.A. Triterpenoid, saponins, oleic acid, vellarin, hydrocotyline, sitosterol, asiatic, madecassic, madasiatic acids, asiaticoside.99 100-115 116311 Treat skin disease, leprosy, antipyretic, detoxicant, diuretic, antirheumatic, mild diuretic, sedative, and peripheral vasodilator. 

A novel dimethyl ester -lactone from Dammar resin has been shown to have the structure (210) by AT-ray analysis. A very probable biogenesis from asiatic acid [(211)— (212) (210)] has been suggested. Madasiatic acid (213), a close relative of asiatic and madecassic acids, has been isolated from Centella asiatica Protection of the vicinal diol system, followed by oxidation to the 6-ketone and Wolff-Kishner reduction yielded 2o,3)5-dihydroxyurs-12-en-28-oic acid. Rubitic... 

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