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Macromolecular drug delivery systems, model

Ahead additional understanding of chitosan-based PEC network development mechanisms, more and more novel drug delivery systems will be produced with tailored applications, particularly the deliveiy systems for macromolecular dmgs e.g. protein and gene delivery. In addition, the in vivo assessment of chitosan-based PEC delivery systems in animal models will be one of the upcoming directions, so as to entirely know their biological fate and in vivo drug delivery effectiveness. [Pg.160]

As for gene delivery, a major obstacle for successful treatment using macromolecular-based therapeutics is endo-lysosomal sequestration of the drugs. Originally, PCI was developed as a dmg delivery system where protein toxins were used as model macromolecular dmgs. [Pg.275]

See other pages where Macromolecular drug delivery systems, model is mentioned: [Pg.1327]    [Pg.312]    [Pg.22]    [Pg.147]    [Pg.8]    [Pg.426]    [Pg.1336]    [Pg.295]    [Pg.2]    [Pg.12]    [Pg.601]    [Pg.8]    [Pg.250]    [Pg.119]    [Pg.858]    [Pg.548]    [Pg.528]   


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