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Macrocyclic kinase inhibitors

Kleiner, R.E., Dumelin, C.E., Tiu, G.C., Sakurai, K., and Liu, D.R. (2010) In vitro selection of a DNA-templated small-molecule library reveals a class of macrocyclic kinase inhibitors. Journal of the American Chemical Society, 132, 11779-11791. [Pg.300]

Figure 5.1 The 3 macrocyclic kinase inhibitors currently in clinical development. Figure 5.1 The 3 macrocyclic kinase inhibitors currently in clinical development.
Designed Macrocyclic Kinase Inhibitors Table 5.7 SAR of substituents in the A-ring."... [Pg.187]

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