Lytic growth

The lytic growth cycle Lysogeny 11 The human immunodeficiency virus... 

Lytic growth of Mu can occur either upon initial infection, if the c gene repressor is not formed, or by induction of a lysogen. In either case, replication of Mu DNA involves repeated transposition of Mu to multiple sites on the host genome. Initially, transcription of only the early genes of Mu occurs, but after gene C protein, a positive activator of late RNA synthesis, is expressed, the synthesis of the Mu head and tail proteins occurs. Eventually, expression of the lytic function occurs and mature phage particles are released. 

Detailed laboratory studies showed that the total length of the lytic growth cycles of the Phaeocystis viruses infecting exponentially growing host cells ranged between 25 and 50 h (Jacobsen et al. 1996 Baudoux and Brussaard 2005). For PpV the latent period, the time period from infection until the first increase in the abundance of extracellular free viruses, was around 12-18 h (Jacobsen et al. 1996). The study by Baudoux and Brussaard (2005) showed three different latent periods for the various PgV isolates in culture, i.e., 10,12 and 16 h (Fig. 3). These periods match the range of latent periods for all characterized phytoplankton viruses so far, and are somewhat... 

The breaking of lysogeny with subsequent lytic growth. 

Renne R, Zhong W, Herndier B, McGrath M, Abbey N, Ganem D (1996) Lytic growth of Kaposi s sarcoma-associate herpesvirus (human herpesvirus 8) in culture. Nat Med 2 342- 346 Rother RP, Rollins SA, Fodor WL, Albrecht JC, Setter E, Fleckenstein B, Squinto SP (1994) Inhibition of complement-mediated cytolysis by the terminal complement inhibitor of herpesvirus saimiri. J Virol 68 730-737... 

Fig. 96. Interaction and subordination of the lambda phage loci during ontogenesis. A hypothetical system controlling together with Cl regulator the selection and the regulation of subprogram of lytic growth or prophage conditions. (After Rather, 1970...

Three loci of the recombination system, two loci of integration, one locus of bacterial metabolic suppression, two loci of duplication, and the Cn and Cm loci which control the selection of developmental pathways (lytic growth vs lysogeny) begin to function within the first 5-7 min. Transcription of the late loci is possible only after circularization of the phage DNA. This conversion of DNA structure, as mentioned above, occurs very early and requires the aid of bacterial ligase. 

Suppressor of amber (UAG) mutation by inserting Tyr. Strains carry the gene tyrT) for tyrosine tRNAl. Required for lytic growth of S7 or SI00 X phage (e.g., Xgtll)... 

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