Lyophilization Technique for Preparing Radiopharmaceutical Kits

Freeze-drying, or lyophilization, is the drying of frozen materials by sublimation, i.e., the direct transition from the frozen state into vapor, without any intermediate liquid phase (Neuman et al 1962). 

The lyophilization technique is the most common method for preparing radiopharmaceutical kits with a prolonged shelf-Ufe. 

Most radiopharmaceutical kits available today are technetium-99m compounds, while a limited number involves indium-113m complexes. Few kits are also used for the preparation of iodine-123 radiopharmaceuticals. 

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Chapter 7 Lyophilization Technique for Preparing Radiopharmaceutical Kits... 

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