Lutetium radioisotope

ISOTOPES There are a total of 59 isotopes of Lutetium. Only two of these are stable Lu-175, which makes up 97.41% of all the natural abundance found on Earth. The other is a long-lived radioisotope (Lu-176) with such a long half-life (4.00x10+ ° years) that it is considered stable Lu-176 contributes 2.59% to the natural abundance of lutetium. 

The present studies were aimed at the development of laboratory evaluation techniques for studying the efficacy of therapeutic radiopharmaceuticals. The primary goal was to develop radiotherapeutic agents using the peptide-BFCA conjugate DOTA-Tyr -octreotate (DOTATATE). The radioisotopes used for the therapeutic preparations were Lu and °Y. Lutetium-177 was identified as an ideal radionuclide for... 

Natural lutetium consists of two isotopes Lu and Lu (Tables 3.11 and 3.12). The latter is actually radioactive, but has an extremely long half-life of 3.78 x 10 years. In total, 34 radioisotopes have been identified, of which, besides Lu, the... 

The use of radioisotopes with long half-lives is less suitable, particularly as regards accuracy and sensitivity even in this case, however, radiometric methods are usually simpler and more rapid than conventional procedures. The basic assumption is that a radioelement has at least one isotope that can be measured hence the isotopic composition must be known. If an element is known to have a constant isotopic composition, measurements and calculations are relatively straightforward (e.g., potassium, rubidium, samarium, lutetium, rhenium, and francium). 

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