Lung cancer oncogenic cell transformation

However, as with many stories in science, caveolin expression and oncogenic transformation are a complex and controversial tale. Indeed, numerous other types of cancer cells display increased caveolin-1 expression. For example, caveolin-1 expression has been reported to be overexpressed in several cancers including prostate and breast [52], lung [53], and bladder [54], to name a few. What to make of the dizzying array of caveolin expression data in the context of cancer from a diagnostic or therapeutic standpoint at this time is unclear. 

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