Low energy CID

Naven, T., Canas, B., Rahman, D., Bardetjones, M., Jeffrey, W., and Pappin, D. (1999). De novo sequencing of peptides by low-energy CID. 47th ASMS Conference, June 13-17, Dallas. 

It has been shown that SID spectra are very similar to high as well as to low-energy CID spectra. [128] The absence of collision gas presents an advantage of... 

Boering, K.A. Rolfe, J. Brauman, J.I. Control of Ion Kinetic Energy in Ion Cyclotron Resonance Spectrometry Very-Low-Energy CID. Rapid Commun. Mass Spectrom. 1992, 6, 303-305. 

Another class of lithium cationized species that were generated and studied are polyglycols. Backbones or molecular chains of functional polyglycols are often difficult to dissociate in tandem mass spectrometers using low energy CID . Apparently, Li+ can... 

Bylka, W., Franski, R., and Stobiecki, M., Differentiation between isomeric acacetin-6-C-(6"-0-malonyl)glucoside and acacetin-8-C-(6"-0-malonyl)glucoside by using low-energy CID mass spectra, J. Mass Spectrom., 37, 648, 2002. 

Low-energy CID spectra are measured using triple quadrupole, ion trap, ICR or hybrid instruments. For tandem mass spectrometers in space, the collision chamber is most often a quadrupole in the RF mode only, which allows one to focus the ions that are angularly dispersed by the collision. The pressure difference between the collision cell and the rest of the analyser is obtained through differential pumping. 

Fragmentation of peptides can also be observed with FTICR instruments. Infrared multiple photon dissociation (IRMPD) and electron capture dissociation (ECD) have been introduced as two alternative dissociation methods to the low-energy CID method. The IRMPD method produces many fragments that make the spectrum very complex and difficult to interpret. Some of the fragment types observed with IRMPD are b and y type ions or these ions that have lost ammonia or water. However, most of them are not these types of fragment ions. 

Low-energy CID of the molecular ions of fatty acid methyl esters obtained by El (70 eV) also has been studied. [286] Such fatty acids methyl esters decompose in the tandem... 

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