Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Lomustine

Lomustine (2-chlorethyl-3 cyclohexyl-1 -nutrosourea, CCNU, Fig 3) is a nitrosourea for oral application. It is used for the treatment of Hodgkin s lymphomas, brain tumors and bronchial carcinomas at a dose of 3.5 mg/kg (130 mg/m2) repeated in 6-8 weeks intervals. [Pg.56]

Carmustine and lomustine can produce remissions that last 3-6 months in 40-50% ofpatients with primary... [Pg.56]

Other subgroups of alkylating agents are the nitrosoureas (examples carmustine, BCNU lomustine, CCNXJ) and the triazenes (example dacarbazine, DTIC). Platinum derivatives (cisplatin, carboplatin, oxaliplatin) have an action that is analogous to that of alkylating agents (formation of crosslinks) and therefore are appended to this class, as well. [Pg.154]

C,7H, N20 93271-68-2) see Praziquantel l-cyclohexyl-5-(4-chlorobutyl)tetrazole (C, H C1N4 73963-42-5) see Cilostazol cyclohexylglyoxylic acid (CSH12O3 4354-49-8) see Cetiedil iV-cyclohexyl-AP-(2-hydroxyethyl)urea (C5HisN202 66929-46-2) see Lomustine... [Pg.2340]

C7H11NO 3/73-53-3) see Acetohexamide Glibenclamide Glipizide Gliquidone Lomustine Talinolol cyclohexylmagnesiiun bromide... [Pg.2340]

C2H7NO 141-43-5) see Alibendol Butethamine Ciclopirox Cloxazolam Flomoxef Haloxazolam loxitalamic acid Ketanserin Levamisole Lomustine Mabuprofen Miltefosine Nicorandil Oxetacaine Phenoxybenzamine Piperazine... [Pg.2372]

Bissery, M. C., Valeriote, F., and Thies, F., In vitro lomustine release from small poly(B-hydroxybutyrate) and poly(D,L-lactide) microspheres, Proc. Int. Symp. Control. Rel. Bioact. Mater., n, 25, 1984. [Pg.38]

Cyclophosphamide (greater than 1 500 mg/m2) Dacarbazine (greater than or equal to 500 mg/m2) Lomustine (greater than 60 mg/m2)... [Pg.302]

Lomustine is an orally available nitrosurea alkylating agent. Lomustine is converted rapidly to the cis- and frans-4-hydroxy metabolites the range of half-lives of these two metabolites is 2 to 4 hours.25 Lomustine has shown clinical activity in the treatment of Hodgkin s lymphoma and melanoma. Side effects are similar to those of carmustine. Patients should receive only enough drug for one cycle at a time to prevent confusion and accidental overdose. [Pg.1290]

Lomustine (CCNU) -nitrosourea alkylating agent cell cycle independent -bone marrow suppression (delayed, prolonged, and cumulative) -nausea and vomiting -pulmonary fibrosis Lung Cancer... [Pg.175]

Alkyl sulfonates busulfan treosulfan aziridines ThioTEPA and TEPA methylmelamine altretamine N-mustards mechlorethamine, chlorambucil, phenylacetic acid mustard, melphalan, prednimustine, estramustine nitrosoureas tallimustine, tauromustine, lomustine/carmustine dacarbazine, temozolomide and mitozolomide... [Pg.113]

Lobendazole, 353 Lometraline, 214 Lomustine, 12, 15 Loperamide, 334 Lorbamate, 21 Loxapine, 427 LSD-25, 476 Lucanthone, 413 Luteolytic activity, 6 Lysergic acid, 475... [Pg.1013]

See other pages where Lomustine is mentioned: [Pg.436]    [Pg.37]    [Pg.84]    [Pg.326]    [Pg.338]    [Pg.270]    [Pg.240]    [Pg.56]    [Pg.584]    [Pg.1183]    [Pg.2328]    [Pg.1290]    [Pg.12]    [Pg.15]    [Pg.15]    [Pg.491]    [Pg.4]    [Pg.4]    [Pg.4]    [Pg.5]    [Pg.183]    [Pg.982]    [Pg.546]    [Pg.251]    [Pg.252]    [Pg.298]    [Pg.342]    [Pg.354]    [Pg.521]    [Pg.521]    [Pg.997]    [Pg.1588]   
See also in sourсe #XX -- [ Pg.1290 ]

See also in sourсe #XX -- [ Pg.12 , Pg.15 ]

See also in sourсe #XX -- [ Pg.19 ]

See also in sourсe #XX -- [ Pg.3 , Pg.4 ]

See also in sourсe #XX -- [ Pg.251 ]

See also in sourсe #XX -- [ Pg.298 ]

See also in sourсe #XX -- [ Pg.2 , Pg.12 , Pg.15 ]

See also in sourсe #XX -- [ Pg.395 , Pg.399 , Pg.400 ]

See also in sourсe #XX -- [ Pg.447 ]

See also in sourсe #XX -- [ Pg.19 , Pg.315 ]

See also in sourсe #XX -- [ Pg.448 , Pg.449 ]

See also in sourсe #XX -- [ Pg.371 , Pg.373 ]

See also in sourсe #XX -- [ Pg.232 ]

See also in sourсe #XX -- [ Pg.84 ]

See also in sourсe #XX -- [ Pg.19 , Pg.315 ]

See also in sourсe #XX -- [ Pg.333 ]

See also in sourсe #XX -- [ Pg.19 , Pg.315 ]

See also in sourсe #XX -- [ Pg.1183 ]

See also in sourсe #XX -- [ Pg.19 , Pg.315 ]

See also in sourсe #XX -- [ Pg.373 , Pg.389 , Pg.389 ]

See also in sourсe #XX -- [ Pg.300 ]

See also in sourсe #XX -- [ Pg.19 , Pg.315 ]

See also in sourсe #XX -- [ Pg.606 ]

See also in sourсe #XX -- [ Pg.519 ]

See also in sourсe #XX -- [ Pg.144 ]

See also in sourсe #XX -- [ Pg.19 , Pg.315 ]

See also in sourсe #XX -- [ Pg.2305 ]

See also in sourсe #XX -- [ Pg.177 ]

See also in sourсe #XX -- [ Pg.360 , Pg.361 ]

See also in sourсe #XX -- [ Pg.84 , Pg.394 , Pg.395 , Pg.605 ]

See also in sourсe #XX -- [ Pg.865 ]

See also in sourсe #XX -- [ Pg.478 , Pg.479 , Pg.486 ]

See also in sourсe #XX -- [ Pg.808 , Pg.809 , Pg.810 ]

See also in sourсe #XX -- [ Pg.124 ]

See also in sourсe #XX -- [ Pg.1156 , Pg.1160 ]

See also in sourсe #XX -- [ Pg.19 , Pg.315 ]

See also in sourсe #XX -- [ Pg.84 ]

See also in sourсe #XX -- [ Pg.13 , Pg.47 , Pg.580 ]

See also in sourсe #XX -- [ Pg.389 ]

See also in sourсe #XX -- [ Pg.603 , Pg.609 ]

See also in sourсe #XX -- [ Pg.426 , Pg.427 ]

See also in sourсe #XX -- [ Pg.468 ]



SEARCH



CeeNU®, lomustine

Cimetidine Lomustine

Lomustine adverse effects

Lomustine alkylating agent

Lomustine pulmonary toxicity

© 2024 chempedia.info