Local deposition fraction

Figure 15 Experimental data on local deposition fraction from 11 young adults Deposition fractions of 1-, 3-, and 5- J,m particles are shown for ten volumetric lung compartments in lung depths between 50 and 500 cml A tidal volume of 500 cm was inhaled from functional residual capacity at flow rates of 150, 250, and 500 cm s" . Error bars ( SE) are shown for a flow rate of 250 cm s. (From Ref 67.)...

As already observed for sublingual administration, even in this case both local retention and systemic absorption of allergen by intestinal tract are likely to occur, the locally retained fraction being higher. Notably the lack of bronchial deposition of radiolabelled Par j 1 seems to minimize the risk of asthma attacks due to undesired bronchial exposure, as previously discussed [5],... 

Figure 14 Modeled local deposition in the tracheobronchial and alveolar region Deposition estimates were earried out for the symmetrical morphometric model of Weibel (5) at a tidal volume of700 cm an inspiratory flow rate of500 em s , and an end-inspiratory pause of 0.5 s. The percentage deposition per airway generation is given for partieles with aerodynamie diameters ranging between 1.6 and 15.8 pm. The percentage quoted is the fraction of all aerosol particles that pass through the glottis. (From Ref. 129.)...

For below one monolayer the deposit may consist of an inhomogeneous mixture of a bare substrate and clusters approximately one monolayer thick. The state with the lowest chemical potential is represented by a line through the origin and tangent to the E[N) curve near the first local minimum, at Ni Nq. The slope of this tangent defines a chemical potential Thus, as N is increased from 0 to the fraction of the sub-... 

Immuno localization using polyclonal antibodies raised against AE showed that AE was widely distributed in orange fruit but with more intensive immunological detection in the outer part of the peels e.g. albedo and flavedo and in the segments (juice vesicles). The results indicate that AE is located at the site where the major fraction of pectin is deposited. 

In The Netherlands locally found clay is almost exclusively used as main raw material. The most important clay deposits for (paving) bricks are found along the river banks of Holland s main rivers. River clay from the polders is mostly fat to very fat and deficient in lime consequently it is used in the production of e g. roof tiles. We call a clay type fat when it contains a high percentage of minute particles. The Dutch coarse-ceramic clay is a sediment, appr. 45 % of whose particles have a diameter of < 10 pm. The coarser sand and silt fractions... 

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