Lithium aplastic anemia with

A 16-year-old with severe aplastic anemia failed to respond to treatment with corticosteroids plus an androgen and to antilymphocyte globulin, but had a strikingly positive response to the combination of lithium and an androgen derivative (41). Leukopenia and thrombocytopenia recurred 2 months after lithium was withdrawn and responded to reintroduction of the drug. 

After he had failed to respond to combined treatment with corticosteroids and androgens and to antilymphocyte globulin, a 16-year-old with aplastic anemia responded to lithium combined with an androgen derivative, relapsed when lithium was stopped, and responded again when it was restarted (41). 

Amano I, Morii T, Yamanaka T, Tsukaguchi N, Nishikawa K, Narita N, Shimoyama T. [Successful lithium carbonate therapy for a patient with intractable and severe aplastic anemia.]Rinsho Ketsueki 1999 40(1) 46-50. 

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