Lipopolymers Langmuir monolayers

Keywords Diffusion, Langmuir monolayer, Lipopolymer, Phospholipid, Viscoelasticity... 

Another model for understanding the diffusion of lipopolymers at the air-water interface in Region II is the free area model, useful for describing the motion of phospholipids on a Langmuir monolayer and many systems where the diffusing particles can be approximated by hard spheres, disks or cylinders [38], In this model, a particle can diffuse in any direction that is free, or in other words, in any direction that is empty of another particle. As would be expected, more crowded or concentrated systems diffuse more slowly. Assuming the particles are at a constant temperature and that other energetic considerations can be described within a constant, D0, this type of diffusion can be expressed as... 

Baekmark TR, Elender G, Lasic DD, Sackmann E (1995) Conformational transitions of mixed monolayers of phospholipids and polyethylene oxide lipopolymers and interaction forces with solid surfaces. Langmuir 11 3975-3987 (correction) (1996) Langmuir 12 4980-4980... 

Baekmark TR, Wiesenthal T, Kuhn P, Albersdorfer A, Nuyken O, Merkel R (1999) A systematic infrared reflection-absorption spectroscopy and film balance study of the phase behavior of lipopolymer monolayers at the air-water interface. Langmuir 15 3616-3626... 

Wiesenthal T, Baekmark TR, Merkel R (1999) Direct evidence for a lipid alkyl chain orderng transition in poly(ethylene oxide) lipopolymer monolayers at the air-water interface obtained from infrared reflection absorption spectroscopy. Langmuir 15 6837-6844... 

Ahrens H, Graf K, Helm CA (2001) Observation of a superstructure X-ray peak within lipopolymer monolayers on the water surface. Langmuir 17 3113-3115... 

Fig. 2 The construction of a polymer-cushioned lipid bilayer membrane. (A) Architecture constructed in a sequential way first, onto the functionalized substrate a polymer layer (cushion) is deposited by adsorption from solution and covalent binding, followed by the (partial) covalent attachment of a lipid monolayer containing some anchor lipids as reactive elements (B) able to couple the whole monolayer to the polymer cushion. (C) Alternatively, a lipopolymer monolayer, organized, e.g., at the water-air interface can be co-spread with regular low-mass amphiphiles and then transferred as a mixed monolayer onto a solid support, prefunctionalized with reactive groups, able to bind covalently to the polymer chains of the lipopolymer molecules, (B). (D) By a fusion step (or a Langmuir Schaefer transfer) the distal lipid monolayer completes the polymer-tethered membrane architecture...

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