Lipolytic genes

Table 3.1 Lipolytic genes identified in metagenome screens.

Sumner, J.M and J.P. McNamara, 2007. Expression of lipolytic genes in the adipose tissue of pregnant and lactating Holstein dairy cattle. J. Dairy Sci. 90, 5237-5246. 

HSL activity was first identified in 1964 as an epinephrine-sensitive lipolytic activity in adipose tissue. It was named according to its property of being activated by hormones such as catecholamines, ACTH, and glucagon [29]. In 1981 the isolation of a relatively pure and biologically active HSL from rat adipocytes was reported [30]. The first cDNA clones were isolated for both rat and human HSL in 1988 [31] and the gene sequence for human HSL was elucidated in 1993 [32]. 

Rosenau F, Jaeger KE (2000) Bacterial lipases from pseudomonas regulation of gene expression and mechanisms of secretion. Biochimie 82 1023-1032 Rubin EM (2008) Genomics of cellulosic biofuels. Nature 454 841-845 Ruiz C, Blanco A, Javier Pastor FI, Diaz P (2002) Analysis of Bacillus megaterium lipolytic system and cloning of LipA, a novel subfamily 1.4 bacterial lipase. EEMS Microbiol Lett 217(2) 263-267... 

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