Lipmann, Fritz

LIPMANN, FRITZ (1899-1986). A German-born biochemist who won the Mobd Prize in 1953 fur the discovery of coeo/yme A (CoA). He earned doctorates ai the L niversit) ol Berlin in hmh chemistry and medicine. He worked at Come)) and Harvard Universities. He founded ihe biochemistry department of Brundeis Unix ersil> and later joined the faculty of Rockleller University. 

Lipmann, Fritz Albert (1899-1986) German/Ameri-can Biochemist Fritz Albert Lipmann was born on June 12, 1899, at Koenigsberg, Germany, to Leopold Lipmann and his wife Gertrud Lachmanski. 

Lipmann, Fritz. (1899-1986). A German-bom biochemist who won the Nobel Prize in 1953 for the discovery of coenzyme A (CoA). He earned doctor-... 

Lipmann, Fritz, Metabolic Generation and Utilization of Phosphate Bond Energy. I... 

Coenzyme A was isolated and identified by Fritz Lipmann an American bio chemist Lipmann shared the 1953 Nobel Prize in physiol ogy or medicine for this work... 

Pantothenic acid is found in extracts from nearly all plants, bacteria, and animals, and the name derives from the Greek pantos, meaning everywhere. It is required in the diet of all vertebrates, but some microorganisms produce it in the rumens of animals such as cattle and sheep. This vitamin is widely distributed in foods common to the human diet, and deficiencies are only observed in cases of severe malnutrition. The eminent German-born biochemist Fritz Lipmann was the first to show that a coenzyme was required to facilitate biological acetylation reactions. (The A in... 

Jan Tuckermann, Peter Herrlich Leibniz Institute for Age Research - Fritz-Lipmann-Institute, Jena, Germany... 

Hans Krebs proposed the cycle in 1937 on the basis of experiments on minced pigeon muscle. He received the Nobel Prize for Medicine and Physiology (jointly with Fritz Lipmann) in 1952. 

Peck then became interested in sulfate-reducing bacteria, which he had got to know in Gest s laboratory. To study the reduction of sulfate. Peck worked in Fritz Lipmann s laboratory in Massachussetts General Hospital (1956) and with Lipmann at Rockefeller University (1957). Lipmann started work on active sulfate in 1954 with Helmut Hilz as a postdoctoral fellow and studied the activation of sulfate to APS and PAPS. Lipmann had left the active sulfate projects by 1957 and started, at Rockefeller University, the studies on protein synthesis. Peck published one paper on the reduction of sulfate with hydrogen in extracts of Desulfovibrio desul-furicans (1959) and one on APS as an intermediate on the oxidation of thiosulfate by Thiobacillus thioparus (1960). 

Fritz A. Lipmann and Hans A. Krebs Physiology/Medicine Coenzyme A, citric acid cycle... 

The existence of a special coenzyme required in biological acetylation was recognized by Fritz Lipmann in 1945.2 3il The joining of acetyl groups to other... 

Phosphopantetheine coenzymes are the biochemically active forms of the vitamin pantothenic acid. In figure 10.11, 4 -phosphopantetheine is shown as covalently linked to an adenylyl group in coenzyme A or it can also be linked to a protein such as a serine hydroxyl group in acyl carrier protein (ACP). It is also found bonded to proteins that catalyze the activation and polymerization of amino acids to polypeptide antibiotics. Coenzyme A was discovered, purified, and structurally characterized by Fritz Lipmann and colleagues in work for which Lipmann was awarded the Nobel Prize in 1953. 

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