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Lipidomics for Health and Disease

Figure 17.1 Schematic illusiTation of Upidomics applications for health and disease. The states A and B represent a pair of conditions for comparison. Ideally, there is only one variable such as a kind of disease, treatment with a nutrient/hormone/dmg, and a genetic mntation between the two states. Lipidomics study could he involved in many processes as indicated with the symbols of. ... Figure 17.1 Schematic illusiTation of Upidomics applications for health and disease. The states A and B represent a pair of conditions for comparison. Ideally, there is only one variable such as a kind of disease, treatment with a nutrient/hormone/dmg, and a genetic mntation between the two states. Lipidomics study could he involved in many processes as indicated with the symbols of. ...
Lipidomics research on cardiovascular disease is multiplexed, including profiling of serum/plasma or myocardial lipidomes, to reveal the underlying molecular mecha-nism(s) leading to the diseases, to assess the effectiveness of nutritional and drug treatments, and to discover and develop possible lipid biomarker for early diagnosis of the diseases as examples. Lipidomics was exploited to understand the biochemical basis of the effectiveness of n-3 PUFA in cardiovascular health [37-39],... [Pg.382]

Sud M, Fahy E, Cotter D, et al. LMSD LIPID MAPS structure database. Nucleic Acids Res. 2007 35 D527-D532. Tajima Y, Ishikawa M, Maekawa K, et al. Lipidomic analysis of brain tissues and plasma in a mouse model expressing mutated human amyloid precursor protein/tau for Alzheimer s disease. Lipids Health Dis. 2013 12 68. Woods AS, Jackson SN. Brain tissue lipidomics direct probing using matrix-assisted laser desorption/ ionization mass spectrometry. AAPS J. 2006 8(2) E391-395. [Pg.103]

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Lipidomes

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