Linustatin

Amarowicz, R., Chong, X., and Shahidi, F. 1993. Chromatographic techniques for preparation of linustatin andneolinustatin from flaxseed Standards for glycoside anlyses. Food Chem. 48,99-101. 

Kurzhals, C., Griitzmacher, H., Selmar, D. and Biehl, B. (1990) Linustatin, the linamarin glucoside protected against cleavage by apoplastic linamarase. Planta Med., 55,673. 

Selmar, D. (1993b) Transport of cyanogenic glucosides linustatin uptake by Hevea cotyledons. Planta, 191,191-9. 

Selmar, D., Lieberei, R. and Biehl, B. (1988) Mobilization and utilization of cyanogenic glycosides the linustatin pathway. Plant Physiol, 86, 711-6. 

The cyanophoric compounds linamarin (11) (/ )-lotaus-tralin (42), (5)-epilotaustralin (43), linustatin (44), neolinus-tatin (45), and sarmentosin epoxide (46) (probable) are derived from valine and isoleucine (Fig. 16.11). The first two compounds are widespread and probably are found in more plant species than any other cyanogenic glycosides. Linamarin and lotaustralin almost always co-occur. These gluco-sides are most commonly encountered in the Asteraceae, Euphorbiaceae, Fabaceae, and Linaceae. 

The corresponding gentiobiosides, linustatin (44) and neolinustatin (45), have been isolated from flax seed and certain Passiflora species (Olafsddttir et al., 1989 Smith et al., 1980 Spencer et al., 1986). 

Smith, C. R., Jr., D. Weislbder, R. W. Miller, I. S. Palmer, and O. E. Olson, Linustatin and neolinustatin Cyanogenic glycosides of linseed meal that protect animals against selenium toxicity, J. Org. Chem., 45, 507-510 (1980). 

Spencer, K., D. S. Seigler, and A. Nahrstedt, Linamarin, lotaus-tralin, linustatin and neolinustatin from Passiflora species. Phytochemistry, 25, 645-647 (1986). 

Unustatin Neolinustatin Unustatin Neolinustatin Linustatin isieolinuslatin... 

Figure 3. Changes of linustatin and neolinustatin content of flaxseed during an 8-day germination period.

Linustatin (66) and neolinustatin (67) are disaccharide derivatives extracted from seeds of Linum usitatissimum (119). Their structural features are closely related to linamarin and lotaustralin, respectively. 

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