Lincosamides and Pleuromutilins

Lincomycin is formulated as a pre-mix and as a soluble powder for addition to drinking water for use in poultry and pigs and is also available in a parenteral formulation for the pig. Oral administration is contraindicated in all mminants because of the risk of bacterial overgrowth with Clostridium species. However, lincomycin is licensed for use parenterally in calves as a combination product 

TABLE 2.3 Milk Plasma Concentration Ratios of AMDs in Lactating Cows  

Drug Drug Class Lipid Solubility P-STa Milk Ultrafiltrate Theoretical Ratio Plasma Ultrafiltrate Experimental Ratio 

PHARMACOKINETICS, DISTRIBUTION, BIOAVAILABILITY, AND RELATIONSHIP TO ANTIBIOTIC RESIDUES 

TABLE 2.4 Tissue Concentrations of Olaquindox after Oral Administration in Chickens (Mean SEM, = 6)  

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