Linckia laevigata

Fig. (14). Structures of Linckosides A-E from the starfish Linckia laevigata...

Evaluation of the neuritogenic activity of five new monoglycosides isolated from the starfish Linckia laevigata demonstrated that the nature of the sugar moiety attached to the side chain seems to be an important factor for the neuritogenic activity. 

A new glucocerebroside, linckiacerebroside A (10) (Fig. 6), together with nearly homogeneous cerebrosides containing phytosphingosine-type long-chain bases and 2-hydroxy fatty acids, was isolated from the starfish Linckia laevigata [46]. 

Linckia laevigata lives in shallow waters of the tropical Indian and Pacific Ocean. The blue carotenoprotein linckiacyanin has been isolated from the skin of starfish. 

Minale et al. have also studied the saponins of L. maculata and have reported isolation of luidiaglycoside A (945), B (946), marthasteroside B (953), C (954), and thomasteroside A (920) 639). Riccio et al. investigated five additional species of starfish, Ophidiaster ophi-dianus 640), Hacelia attenuata 640), Linckia laevigata 641), Protoreaster nodosus 642), and Pentaceraster alveolatus 642). O. ophidianus and H. attenuata both contained two saponins with a C26 steroidal aglycone, named ophidianoside B (955) and C (956). Two further saponins... 

Minale, L., C. Pizza, R. Riccio, F. Zollo, J. Pusset, and P. Laboute Starfish Saponins, XIII. Occurrence of Nodososide in the Starfish Acanthaster planci and Linckia laevigata. J. Nat. Prod. 47, 558 (1984). 

Riccio, R., O. Squillace-Greco, L. Minale, J. Pusset, and J.L. Menou Starfish Saponins, Part 18. Steroidal Glycoside Sulfates from the Starfish Linckia laevigata. J. Nat. Prod. 48, 97 (1985). 

Linckia laevigata Riccio, Squillace-Creco, and Minale, 1985d... 

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