Limitations or disadvantages

The obstacles, limitations or disadvantages confronting acceptance of plastics are ... 

The tritiation procedures given in Table 18.1 all have serious limitations or disadvantages. Thus, for all three hydrogen isotope exchange reactions, HTO is used as the donor. For health and safety reasons 50 Ci mL (1 Ci = 37 GBq), corresponding to dose on 2% isotopic abundance, is the highest specific activity that we have used and this inevitably limits the maximum specific activity of the products that can be obtained via these routes. 

There are limitations and disadvantages to the bolus approach, however. Only a limited volume may be injected, which may prohibit the use of bolus when volumes to be introduced are high (due to, e.g., low active compound solubility or a host of other reasons). Only two devices (syringe and catheter) are available for use in the bolus approach. If a multiple-day course of treatment is desired (say, every day for 15 days), separate injections must be made at discreet entry sites. 

The relative precision of electrothermal methods is generally in the range of 5% to 10%, compared with the 1% or better that can be expected for flame or plasma atomization. Furthermore, furnace methods are slow and typically require several minutes per element. Still another disadvantage is that chemical interference effects are often more severe with electrothermal atomization than with flame atomization. A final disadvantage is that the analytical range is low, usually less than two orders of magnitude. Consequently, electrothermal atomization is ordinarily applied only when flame or plasma atomization provides inadequate detection limits or when sample sizes are extremely limited. 

Anderson. Each of these methods has advantages or disadvantages, depending on the system being considered, and can, in any case, only be applied over a limited temperature-range. It is preferable to use several of the methods, each for the appropriate temperature-range, and, hence, minimize any systematic errors. 

Each source of water has inherent qualities and limitations. Decide which is an advantage or disadvantage to you. 

Finally, the crystallization behavior of the remarkably stable Si-B-N-C fiber must be studied under anticipated service conditions in order to determine the limits of the material and to establish its comparative advantages or disadvantages over other non-oxide fibers. 

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