Lilium maximowiczii, chlorinated

Chlorinated orcinol derivatives have been isolated from diseased bulbs of the edible lily Lilium maximowiczii. The antifungal activity of these compounds was tested against Bipolaris leersiae. Inhibition of the conidial germination depends on the number of chlorine atoms in the compounds. The trichlorinated orcinol 156 shows the highest activity. Dichlorinated orcinols, e.g. 157, are next, and the monochlorinated ones, e.g. 158, are still less active. The nonchlorinated orcinol shows lowest activity [121]. 

Fig. 3.26 Lilium maximowiczii, the edible Japanese lily that produces the seven chlorinated fungicides 1783-1789 the brown portion indicates disease by a Fusarium fungus (Photo K. Monde)...

Monde K, Satoh H, Nakamura M, Tamura M, Takasugi M (1998) Organochlorine Compounds from a Terrestrial Higher Plant Structures and Origin of Chlorinated Orcinol Derivatives from Diseased Bulbs of Lilium maximowiczii. J Nat Prod 61 913... 

Chlorinated ordnols have been identified from the bulbs of the edible lily (Lilium maximowiczii) infected with the fungus Fusarium oxysporum f.sp. lilii. They were not, however, fungal metabolites these could also be induced by ultraviolet radiation of bulb scales, and the more highly chlorinated metabolites inhibited conidial germination of Bipolaris leersiae (Monde et al. 1998). 

Monde, K., H. Satoh, M. Nakamura, M. Tamura, and M. Takasugi. 1998. Organochlo-rine compounds from a terrestrial plant structures and origin of chlorinated orcinol derivatives from diseased bulbs of Lilium maximowiczii. ]. Nat. Prod. 61 913-921. 

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