Ligand saturation

Lewis Bases. A variety of other ligands have been studied, but with only a few of the transition metals. There is still a lot of room for scoping work in this direction. Other reactant systems reported are ammoni a(2e), methanol (3h), and hydrogen sulfide(3b) with iron, and benzene with tungsten (Tf) and plati num(3a). In a qualitative sense all of these reactions appear to occur at, or near gas kinetic rates without distinct size selectivity. The ammonia chemisorbs on each collision with no size selective behavior. These complexes have lower ionization potential indicative of the donor type ligands. Saturation studies have indicated a variety of absorption sites on a single size cluster(51). 

Scatchard plots for ligand saturation behavior of an oligomeric protein exhibiting positive cooperativity, negative cooperativity, or independent binding behavior. For addition details, See Monod-Wyman-Changeux Cooperativity Model Scatchard Plot... 

The ligand saturation function accounts for the moles of bound... 

Figure 1. Derivation of the MWC ligand saturation equation for a dimeric protein.

Figure 2. Top Effect of the magnitude of the allosteric constant on ligand saturation behavior of a dimer obeying the MWC model. Bottom Fraction of total dimeric protein present in various T- and R-species.

Figure 3. Free energy diagram for ligand binding interactions to an MWC dimer. Note that the relative stability of the To to Rq alters the ligand saturation curve as shown in each graph. The energy changes between each R-state are equivalent because each ligand binding interaction has the same equilibrium constant.

S-type describes adsorbate-adsorbate interactions on the adsorbent, often referred to as clustering, and/or the interaction of the adsorbate with solution ligands. When ligand saturation is reached, adsorption proceeds (e.g., aluminum-ful vie acid-clay interactions)... 

Once differences in structure amplitudes, AF, have been obtained by comparison of the diffraction data from ligand-saturated and native crystals, a Fourier synthesis can be computed in the normal way with phase angles calculated from the protein structure alone. These phases are not exactly the phases that should be attached to the observed differences forming the Fourier coefficients. The correct phases would be those calculated from the ligand correctly disposed in the crystal unit cell, which is, of course, what is being sought, what is not known. Using phases calculated from the native structure in conjunction with... 

The STD-NMR experiment is carried out such that ligand saturation, effected when the ligand is bound to the protein, is actually measured on the free ligand, not the bound-state ligand. This is achieved by requiring that the... 

Figure 6 Two bis-pyridylimine ligands saturate the coordination of three-coordinate Ag ions in a planar...

In this case, the bidentate ligand saturates the eight coordination sites of thorium, i.e., the complex contains no water at all. This makes it hydrophobic and gives high D values. 

Ru and Fe complexes in which two bipy ligands saturate the hexacoordination at PVP or PVbipy chains are among the most conmuMi residues they were also obtained on the electrode stuface by direct cathodic reduction of the relevant monomer, as reported in the already cited Ref. [8]. 

It was reported that the high binding affinity between BPT and the immobilized antibody meant t t once bound ligand saturated the antibodies, each tip was no longer active and had to be replaced. Practically, this allowed only one run for each tip fabricated. Because of this, calibration of the sensor response had to be done with many sensors prepared under similar conditions and not wi the actual sensor used in the experiment. 

TROSY spectra, ligand-saturated EmrE exists in... 

Ligands Saturate Dangling Bonds and Accelerate Electron-Phonon Relaxation... 

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