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Ligand-based screening techniques

An extension of this FTICR mass spectrometry-based screening technique has been to screen a combinatorial library for ligands to two receptors simultaneously (59, 60). In this example, the two receptors consisting of RNA constructs representing the prokaryotic (16s) rRNA and eukaryotic (18s) rRNA A-site were incubated simultaneously with an aminogly-... [Pg.601]

Good, A.C. and Cheney, D.L Analysis and optimization of stmcture-based virtual screening protocols (1) exploration of ligand conformational sampling techniques. /. Mol. Graph. Model. 2003, 22, 23-30. [Pg.104]

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Based Screens

Ligand-based

Ligand-based screening

Screening techniques