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Library design target class-specific

Another important class of targeted libraries is aimed at specific families of targets. Examples are kinases (125, 126), proteases (127-129), and G-protein coupled receptors (130, 131). These libraries are driven by generic structural information on the family of proteins, and the correct use of this information (creation of a loose pharmacophore, selection of monomers/products on the basis of the similarity fit into the pharmacophoric model) is similar to the process observed for focused library design. [Pg.200]

See other pages where Library design target class-specific is mentioned: [Pg.362]    [Pg.360]    [Pg.396]    [Pg.181]    [Pg.182]    [Pg.183]    [Pg.298]    [Pg.356]    [Pg.364]    [Pg.365]    [Pg.368]    [Pg.136]    [Pg.4]    [Pg.142]    [Pg.158]    [Pg.161]    [Pg.343]    [Pg.344]    [Pg.176]    [Pg.100]    [Pg.222]    [Pg.311]    [Pg.228]    [Pg.4014]    [Pg.27]    [Pg.48]    [Pg.40]    [Pg.514]    [Pg.956]    [Pg.483]    [Pg.60]    [Pg.259]    [Pg.273]    [Pg.141]    [Pg.69]    [Pg.409]    [Pg.180]    [Pg.5]    [Pg.132]    [Pg.43]    [Pg.17]    [Pg.96]    [Pg.22]    [Pg.43]    [Pg.958]    [Pg.21]    [Pg.214]    [Pg.319]    [Pg.86]    [Pg.72]   
See also in sourсe #XX -- [ Pg.355 ]



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Class 1 target

Library design

Library design targeted

Library target class

Library targeted libraries

Specific designs

Target libraries

Target specifications

Target, targets classes

Target, targets libraries

Target-specific

Targeted libraries

Targeting specificity

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