Leucaena glauca

Degradation of the toxin mimosine, which is produced by Leucaena glauca and Mimosa pudica, is initiated by the formation of 3-hydroxypyrid-4-one, plausibly by the activity of... 

Leucaenine (leucenol), C8H10O4N2 (506), is the active principle of the seeds of Leucaena glauca Benth. (503). It is prepared from an aqueous... 

Acid Sequences of Ferredoxins from Leucaena glauca J. Biol. Chem. (1969) 244,955. 

The (25,5/J)-form trans-c-) of 5-H. occurs is Rhapis excelsa (Palmae) and ripe dates, Leucaena glauca, Gymnocladus dioicus, mulberry leaves Moms alba), and in the seeds of Caesalpinia species. Mp. 210-215 °C (decomp.), [a]g -10.9° (H O). The... 

Isol. from Ononis spp., Vigna catjang, Kiggelaria africana, Medicago saliva (alfalfa), Leucaena glauca and others. 

A vivid example of the value of perspicacity in drug development is provided by the evaluation of mimosine (Q) as an antitumor agent. Because sheep eating /= the browse tree, Leucaena glauca, shed their wool and expe-... 

CgH oN204, Mr 198.18, mp. 225 °C, [a -20° (HjO). A non-proteinogenic amino acid in seeds and leaves of Leucaena spp. and Mimosa spp. (Mimosaceae). M. is identical with leucenol. Leaves of L. leucocephala L. glauca) contain 2-5% M. (dry weight). Seeds of L. leucocephala and M. pudica also contain the 3 -0-P-D-glucosyl derivative (mimoside). 

The pyridine (dihydropyridine) derived amino acid P-(3-hydroxy-4-pyridon-l-yl)-L-alanine, L-mimosine (2-62), is thyreotoxic (causes over-activity of the thyroid gland) to nonruminant animals. It occurs in the subfamily Mimosoideae of the legume family Fabaceae, in plants of the genera Mimosa and Leucaena. Leucaena leucocephala (syn. Mimosa glauca) is native to the tropical and subtropical Americas, known as White Leadtree, and is used as livestock fodder. The mimosine content in seeds can reach up to 5% of dry matter (see Section 10.3.2.7.1). The amino acid pyridosine arising from lysine in the Maillard reaction can also be considered a dihydropyridine derivative (see Section 4.7.5.12.3). 

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