Lethal dosage

Toxicity. The U.S. Eood and Dmg Administration regards common salt, ie, NaCl, as GRAS for its intended use as a food additive. Oral toxicity for mammals is reported in mg/kg (16) for humans, TD qI 12,357 23D-C (daily-continuous) for mice, LD qI 4000 for rats, LD qI 3000 and for rabbits, LD qI 8000. TD q and LD q are lowest level toxic and lethal dosages, respectively. 

No specific information but, like related compounds, PD is probably detoxifies rapidly in sub-lethal dosages. 

Symptoms appear much more slowly from skin absorption. Skin absorption great enough to cause death may occur in 1-2 h. Respiratory lethal dosages kill in 1-10 min, and liquid in the eye kills nearly as rapidly. Very small skin dosages sometimes cause local sweating and tremors but little other effects. Nerve agents are cumulative poisons. Repeated exposure to low concentrations, if not too far apart, will produce symptoms. 

Median Lethal Dosage (LDS0) of Liquid Agent... 

Median Lethal Dosage (LCt50) of a Vapor or Aerosol... 

Figure 1. Relation among Log k of Dehydrochlorination Reaction, Median Lethal Dosage to Mosquito Larvae, and Substituent Constant for Trichloroethyl Compounds...

The data used are given in Table I. The elimination rate constants included were determined at 20° C. (5). The toxicity to mosquito larvae, given as median lethal dosages (concentration in parts per million of water required to cause 50% mortality in 48 hours), was estimated from the data of Deonier et al. (9) and is probably reproducible to within 30%. 

Median Lethal Dosage (LD50) The lethal dose of a poison, when taken orally or absorbed through the skin, which is lethal to 50 percent of the exposed laboratory animal population. 

Median Lethal Dosage (mg-min/m3) 3,000-5,000 by inhalation 100,000 by skin exposure. 

Median Lethal Dosage, Animals LD50 (monkey, percutaneous) = 9.3 mg/kg (shaved skin) LCt50 (monkey, inhalation) = 187 mg-min/m3 (t = 10)... 

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