Lert.-Butyl-

Calcium hydride, for drying of lert-butyl alcohol, 41, 7 CARBODIIMIDE, DrPHENYL-, 43, 31 Carbodiumdes, from isocyanates, 43, 31... 

N,N-Dimethylamlme, condensation with oxyalyl chloride, 41, 1 in reaction of cyanoacctyl chloride and lert-butyl alcohol, 41, 6 N-(2,4-Dimethylbenzyl)-acetamide, 42, 18... 

Dipping solution I may be stored in the refrigerator for a few days. lert-Butyl hypochlorite should be stored cool in the dark under an atmosphere of nitrogen. 

Prepare anhydrous lert.-butyl alcohol by refluxing the commercial product with sodium (ca. 4 g. per 100 ml.) until the metal is about two-thirds dissolved and then distilling. Free metal should be present during the distillation. 

The allylic HYCRAM derivative was subsequently modified by insertion of a standard amino acid between the aminomethyl resin and the hydroxy butenoic acid moiety. Using this allylic anchor, the resin-linked, glycosylated HIV peptide T-derivative 164 was synthesized by application of Fmoc amino protection and sidechain protection with lert-butyl groups. The lac-tosamine peptide T (165) could be released from the resin by application of the palladium(0)-catalyzed allyl-transfer reaction to V-methyl aniline as the allyl acceptor. 

The rearrangement with ring contraction probably is the most important synthetic application of the Favorskii reaction it is for example used in the synthesis of steroids. Yields can vary from good to moderate. As solvents diethyl ether or alcohols are often used. With acyclic a-halo ketones bearing voluminous substituents in a -position, yields can be low a lert-butyl substituent will prevent the rearrangement. 

Bis[(/[i -tert-butylperox-0,0)(di-lert-butyl)gallium(III)] (40) (PAJKIU)... 

The Sharpless epoxidation of allylic alcohols with lert-butyl hydroperoxide/titanium tetraiso-propoxide/diisopropyl tartrate (DIPT) is a highly enantioface-selective reaction and follows the topicity shown51. 

Tab. 79 N-For my 1-N-[2.3.4.6-t etra-0-(2,2-dimet hyl-propanoyl )-/J-D-galactopy ranosyl]-(/J)-2-amino-carbonsaure-N-lert.-butyl-amide I und (R)-2-Amino-carbonsauren 11 durch...

Dimethyl(phenyl)methylperoxy] hydrogen[tris(3-lert-butyl-5-isopropylpyrazol-l-yl]borato manganese(II) (HIZDTD) Group 8 1.410 1.463 176.9 126... 

The commercial constant boiling point alcohol, b.p. 80°/760 mm., containing 88 per cent, of lert.-butyl alcohol, may be used 28 5 g. are required. 

Finally may be mentioned the report hy Maruyama and oo-aorveiK1 that ets- and ( m -stilbene both yield the trana epoxide on licmmcrrt with lert-butyl hydroperoxide (Eq. 83a), the latter reaetiin m"n rapidly. 

Di-lert.-butyl-3-(hexafluoro-isopropyliden)-6-oxo- E10b2. I 11 ( IIC1 > Trien on)... 

The oxidation is conducted in a two-phase system with lert-butyl alcohol as the organic phase. The advantage of this procedure is that osmium tetroxidc (37) is the only oxidizing agent that enters the organic phase. 

Alkenes of molecular formula C12HM are trimers of 2-methylpropene. The first molecule of 2-methylpropene is protonated to form lert-butyl cation, which reacts with a second molecule of 2-methylpropene to give a tertiary carbocation having eight carbons. 

Chemical names original NA 4-amino-6-lert-butyl-3-(methylthio)- as-triazine-5(47T)-one 2-methoxy-4,6-bis(isopropyl amino)-s-triazine... 

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