Lens comfort solutions

Among the polymers used in lens comfort solutions are polyvinyl alcohol, polyvinylpyrrolidone, dextran, and various cellulose derivatives such as hydroxyethyl cellulose, hydroxypropyl cellulose, and hydroxypropyl methylcellulose. Surfactants include certain poloxamer and poloxamine compounds. Other normal components comprise appropriate preservative(s) as well as buffering and tonicity-adjusting agents. 

Marketed lens care products fall mainly into the following categories cleaners, disinfectants, lubricants, and multipurpose products. Cleaners are subdivided into daily or weekly cleaners. Disinfectants comprise solutions containing chemical antimicrobial agents, which do not require heating the lenses, and preserved or unpreserved saline solutions, which are used with an electrical thermal device for lens disinfection. These products are also used to rinse contact lenses. Lens lubricants are intended to enhance the comfort of lens wear and are used prior to insertion and during wear. Multipurpose solutions are intended to accomplish... 

Lens care product components have the potential to affect the physiological response and comfort of Si-Hy CLs. The most common cHnical presentation of the chemical interaction between CL solutions and the ocular surface is the so-called solution-induced corneal staining (SICS) that has been observed with Si-Hy CL, particularly when PHMB-preserved care solutions are used (Figure 19.6). It has been observed that Si-Hy materials when used with care systems containing... 

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