Lauroyl choline

In orientating toxicity studies palmitoyl-DL-carnitine chloride and lauroyl choline were shown to cause only slight alterations of the mucosal cell structure of jejunum and colon under prolonged exposure when being tested in permeation-enhancing concentrations (LeCluyse et al. 1993 Fix et al. 1996). In another study on Caco-2 monolayers, however, palmitoyl-DL-carnitine chloride caused LDH release, increased uptake of propidium iodide and reduced neutral red retention, in concentrations needed to provide an improved uptake of PEG 4000 (Duizer et al. 1998). 

Acyl carnitines and cholines Palmitoyl carnitine, lauroyl choline... 

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