Laurence-moon-biedl syndrome

Green, J.S., Parfiey, P.S., Harnett, J.D., Farid, N.R., Cramer, B.C., Johnson, G., Heath, O., McManamon, P.J., O Leary, E. and Pryse-Phillips, W. (1989) The cardinal manifestations of Bardet-Biedl syndrome, a form of Laurence-Moon-Biedl syndrome. N. Engl. J. Med. 321, 1002-1009. 

Prader-Willi syndrome Laurence-Moon-Biedl syndrome GiiRH deficiency (KaUmanns syndrome)... 

Hypopituitarism may involve all the hormones of the anterior hypophysis, or it may be restricted to one or a few hormones of the anterior lobe, depending on the patient s age. General hypopituitarism of the anterior lobe results in pituitary dwarfism, infantilism, and Simmonds cachexia. The restricted forms of hypopituitarism lead to well-known clinical syndromes such as Frohlich s and the Laurence-Moon-Biedl syndrome. 

The Laurence-Moon-Biedl syndrome is a familial disease characterized by adiposogenital dystrophy, mental deficiency, and numerous other congenital malformations, including skull deformities, atresia of the anus, polydactyly, and retinitis pigmentosa. 

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