Medical diagnostics lanthanide ions

The discussed examples clearly demonstrate the importance of azamacrocycles as structural element to create supramolecular function. Their rigid structure, the basicity and transition metal-ion coordinating ability make them suitable as scaffolds and binding sites. Lanthanide chemosensors containing azamacrocyclic ligands have already reached applications in medical diagnostics. Other applications of azamacrocyclic systems with supramolecular functions, particularly in biochemistry, will follow. 

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