Lamotrigine characteristics

Outlook Among the newer antiepileptics, gabapentin, oxycarbazepine, lamotrigine, and topiramate are now endorsed as primary monotherapeutics for both partial and generalized seizures. Their pharmacokinetic characteristics are generally more desirable than those of the older drugs. 

Simple partial seizures can have the characteristics described in this patient. The Jacksonian march is due to progression of epileptiform discharges in the contralateral motor cortex. Phenytoin, carbamazepine, primidone, and lamotrigine are effective in partial seizures. The succinimides (ethosuximide, phensuximide) are not effective in partial seizures or in generalized tonic-clonic seizure states. The answer is (B). 

Lamictal (Lamotrigine). GlaxoSmithKline UK. UK Summary of product characteristics,... 

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