Lactose biosynthesis

DGBP Lactalbumins Lysozymes Galactose activation (369) Lactose biosynthesis Catalyze degradation of peptidoglycan, e.g. of bacterial cell walls (370,371)... 

Lactose biosynthesis in the mammary gland has been the subject of a considerable volume of published work which has been reviewed (Ebner and Schanbacher 1974 Jones 1978). Much of the following discussion is taken from these two references. 

Jones, E. A. 1978. Lactose biosynthesis. In Lactation A Comprehensive Treatise, Vol. IV. B.L. Larson (Editor). Academic Press, New York, pp. 371-385. 

The over-all scheme of lactose biosynthesis is probably as follows, the enzyme catalyzing each step appearing in parentheses. 

The Dual Role of p4-Galactosyltransferase-I (p4GalT-I) in Oligosaccharide and Lactose Biosynthesis The Early Days... 

Charron, M., Shaper, J.H. and Shaper, N.L. The increased level of pi,4-galactosyltransferase required for lactose biosynthesis is achieved in part by translational control. Proc. Natl Acad. Sci. U.S.A. 1998, 95, 14805-14810. 

While cellobiose is a poor inducer, lactose, the milk sugar, is a good inducer of cellulase biosynthesis. Lactose-induced fungus produces a cellulase complex which is identical to those cellulases induced by cellulose (for SDS gels see Figure 9b, e, h, i). 

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