Lactic acid factors affecting

Kader A, Jalil R. Formulation factors affecting drug release from poly(lactic acid)(PLA) microcapsule tablets. Drug Dev Ind Phann 1999 25(2) 141 151. 

Nomura, Y., Yamamoto, K., andlshizaki, A. 1991. Factors affecting lactic acid production rate in the built-in electrodialysis fermentation an approach to high speed batch culture. J. Ferment. Bioeng. 71, 450-452. 

Hofvendahl, K. and Hahn-Hagerdal, B. 2000. Factors Affecting the Fermentative Lactic Acid Production from Renewable Resources. Enzyme Microb. Technol., 26, 87-107. 

Besides the production of L-lactic acid, the fermentation process can simultaneously produce various other metabolites such as acetic acid, f umaric acid, ethanol, malic acid, etc. However, the amount of these metabolites can have a significant influence on the downstream process and the quality of the L(+)-lactic acid produced (Wang et al., 2005). Fumaric acid is the main by-product and its accumulation is affected by many factors,... 

Fig. 15.11 Factors affecting pH after a 10% glucose or sucrose mouth rinse. Dashed line indicates pH 7. Vectors 1 and 4 increase the pH vectors 2 and 3 decrease the pH. The short-chain carboxylic acids (SCCA) may be produced from amino acids along with ammonia, or from the catabolism of lactic acid (see text and also Fig. 1.8). (From Fig. 9 in Kleinberg I, 2002. A mixed-bacterial ecological approach to understanding the role of the oral bacteria in dental caries causation an alternative to Streptococcus mutans and the specific-plaque hypothesis. Crit Rev Oral Biol Med 13 108-125)...

Williams, A. G., Noble, J., Tammam, J., Lloyd, D., Banks, J. M. (2002). Factors affecting the activity of enzymes involved in peptide and amino acid catahohsm in non-starter lactic acid bacteria isolated from Cheddar cheese. International Dairy Journal, 12, 841-852. 

Guerra, N. R, Rua, M. L., Pastrana, L. (2001). Nutritional factors affecting the production of two bacteiiocins from lactic acid bacteria on whey. International Journal of Food Microbiology, 70(3), 267-281. 

Hofvendahl K, Hahn-Hagerdal B. (2000). Factors affecting the fermentative lactic acid production from renewable resources. Enzyme Microb Technol, 26, 87-107. 

Hood, A.V. 1984. Possible factors affecting sulfur dioxide inhibition of lactic acid bacteria in newly-fermented wines. Malolactic Fermentation. Aust. Soc. for Viticulture and Oenology, Inc. 

Drug release rate is affected by many factors, such as polymer composition, molecular weight, and particles size. Polymers such as poly(lactic acid), poly(glycolic acid), poly(lactic-co-glycolic acid), and polyalkylcyanoacrylates have been tested for this purpose (Batycky et al., 1997, Liggins and Burt, 2001, Siepmann et al., 2002, Park, 1995, Dossi et al., 2010, Freiberg and Zhu, 2004). However, devices can also be film-shaped or disc-shaped... 

Alexis, F., 2005. Factors affecting the degradation and drug-release mechanism of poly(lactic acid) and poly[(lactic acid)-co-(glycolic acid)]. Polym. Int. 54, 36—46. 

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