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Lactate dehydrogenase inhibition

Anderson BM, Noble C Jr. 1977. In vitro inhibition of lactate dehydrogenases by Kepone. J Agric Pood Chem 25(l) 28-31. [Pg.235]

Hendrickson CM, Bowden JA. 1975. The in vitro inhibition of rabbit muscle lactate dehydrogenase by mirex and Kepone. J Agric Food Chem 23 407-409. [Pg.260]

Hendrickson CM, Bowden JA. 1976. In vitro inhibition of lactate dehydrogenase by insecticidal polychlorinated hydrocarbons I. Mechanism of inhibition Possible association of reduced nicotinamide adenine dinucleotide with mirex. J Agric Food Chem 24(2) 241-244. [Pg.260]

ISOTOPE EXCHANGE AT EQUILIBRIUM ISOTOPE TRAPPING LACTATE DEHYDROGENASE LIGAND EXCLUSION MODEL NONPRODUCTIVE COMPLEXES PRODUCT INHIBITION SUBSTRATE INHIBITION... [Pg.717]

ISOTOPE TRAPPING STICKY SUBSTRATES Substrate-induced conformational change, INDUCED FIT MODEL SUBSTRATE INHIBITION ABORTIVE COMPLEX FORMATION LACTATE DEHYDROGENASE LEE-WILSON EQUATION... [Pg.782]

Timbrell et al. (1996) reported that much higher hydrazine concentrations were required in rat hepatocyte cultures in comparison to plasma concentrations in male Sprague-Dawley rats to elicit the following hepatic/hepatocellular effects lactate dehydrogenase leakage, ATP and GST depletion, increase in citrulline level, protein synthesis inhibition, taurine leakage and triglyceride accumulation. [Pg.996]

The reactions of Eq. 15-19 occur nonenzymatically only under the influence of strong base but dehydrogenases often catalyze similar condensations relatively rapidly and reversibly. Pyruvate inhibits lactate dehydrogenase, 2-oxoglutarate inhibits glutamate dehydrogenase, and ketones inhibit a short-chain alcohol dehydrogenase in this manner.133,693... [Pg.780]

Elevated pyruvate concentration inhibits the heart muscle lactate dehydrogenase (LDH) isoenzyme but not the skeletal muscle LDH isoenzyme. [Pg.279]

Pentachlorophenol CoPC-SPCE competitive inhibition of lactate dehydrogenase using NADPH as a co-factor 20... [Pg.522]

K. M. Moreton, and J. J. Holbrook, Removal of substrate inhibition in a lactate dehydrogenase from human muscle by a single residue, FEBS Lett. 1996, 399, 193-197. [Pg.306]

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See also in sourсe #XX -- [ Pg.25 ]



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