Glucitol l,4:3,6-dianhydro-D-, 2,5-dinitrate

Circular dichroism of the nitrato (ONO) chromophore of the mono- and di-nitric esters of l,4 3,6-dianhydrohexitols was found to consist of two dichroic bands, one weak and positive, at about 265 nm, and a stronger band at —228 nm, which was positive for the endo-(R)-nitrato chromophore and negative for the exo-(S)-nitrato group.68 However, for l,4 3,6-dianhydro-D-glucitol dinitrate, which has both an endo and an exo nitrato group, both bands were positive, but [ ]ma r (+ 7,260) for the band at 225 nm was about half of the algebraic sum of this band for the di-endo (+ 18,400) and di-exo (—4,460) compounds. 

Diammonium Aquabis(peroxotartratovanadate)(2-), 3065b l,4 3,6-Dianhydro-D-glucitol dinitrate, see Isosorbide dinitrate, 2373 Dianilineoxodiperoxochromium(VI), 3517 Dianilinium dichromate, 3531... 

The properties, synthesis, stability, and metabolism of l,4 3,6-dianhydro-D-glucitol dinitrate have been discussed. The i.r. and Raman spectra of powdered 1,5-anhydro-xylitol, -ribitol, and -L-arabinitol have been reported Raman spectra were also recorded for solutions of the anhydro-sugars in water and in [ HeJDMSO. ... 

The synthesis of l,4 3,6-dianhydro-D-glucitol 5-nitrate from the 2,5-dinitrate is covered in Chapter 18. 

Isosorbide (1,4 3,6-dianhydro-D-glucitol), a metabolite of iso-sorbide dinitrate, has been determined in urine by capillary g.l.c. of its heptafluorobutyrate derivative with electron-capture... 

D-Glucitol hexanitrate256 and the pentanitrates of xylitol,257 ribitol,257 and L-arabinitol257 have been partially denitrated by the action of pyridine, but the structures of the reaction products were not ascertained. The dinitrates of the 1,4.3,6-dianhydro derivatives of D-mannitol, D-glucitol, and L-iditol react only slowly in anhydrous pyridine,258 and only traces of mononitrates could be detected in aqueous pyridine, mononitrates accounted for a maximum of 10% of the decomposed dinitrates. 

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