L-Glucitol

Lemer (29) reported a simple synthesis of L-erythrose that involves 2,3-di-O-isopropylidene-D-gulono-1,4-lactone (7b) as a key intermediate. Reduction of the lactone group of 7b with sodium borohydride, followed by periodate oxidation of the L-glucitol derivative, afforded 2,3-O-isopropy-lidene-L-erythrose. The free sugar may be readily obtained by acidic hydrolysis of the latter. 

Six sugar-mimicking alkaloids such as 1-deoxynorjirimycin (4), 1,4-dideoxy-l,4-imino-D-ribitol (8), 2,5-imino-l,2,5-trideoxy-L-glucitol (9),... 

L-Glucitol (n-gulitol), the enantiomorph of sorbitol, has been obtained by the action of sodium amalgam on D-gulonolactone or, along with D-iditol, on D-sorbose. ... 

Brechtel, E. Huwig, A. Giffhorn, R L-Glucitol catabolism in Stenotropho-monas maltophilia Ac. Appl. Environ. Microbiol., 68, 582-587 (2002)... 

Bacterial oxidation of L-mannitol and L-glucitol has been used to prepare L-fructose and D-sorbose respectively. The bacterium called MD 13 contains a novel polyol dehydrogenase which preferentially oxidizes L-alditols. The reaction was also applied to pentltols. 

S,6-Diisopropylidene 1-Deoxy-3,4 5,6-di-O-isopropylidene-L-glucitol. 6-Deoxy-l,2 3,4-di-0-isopropylidene-D-gulitol Q2H22O5 246.303 Light yellow syrup. [a]o -1 (c, 1.00 in MeOH). 

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