L-amino-4-nitrobenzene

Synonyms AI3-08926 AIDS-19458 l-Amino-4-nitrobenzene 4 Aminonitrobenzene jO-Amino nitrobenzene Azoamine red ZH Azofix Red GG salt Azoic diazo component 37 BRN 0508690 C-02126 CCRIS 1184 C.I. 37035 C.I. azoic diazo component 37 C.I. developer 17 Developer P Devol red GG Diazo fast red GG EINECS 202-810-1 Fast red base GG Fast red base 2J Fast red 2G base Fast red 2G salt Fast red GG base Fast red GG salt Fast red MP base Fast red P base Fast red P salt Fast red salt GG Fast red salt 2J IG base Naphtolean red GG base NCI-C60786 4-Nitraniline jo-Nitraniline Nitrazol 2F extra jo-Nitroaniline para-Nitroaniline 4-Nitrobenzenamine p-Nitrobenzenamine 4-Nitrophenylamine p-Nitrophenylamine PNA RCRA waste number P077 Red 2G base Shinnippon fast red GG base UN 1661. 

Synonym l-amino-4-nitrobenzene, p-aminonitrobenzene, />nitroaniline, 4-nitrobenzenamine, 4-nitrophenylamine... 

SYNS p-AMNONITROBENZENE l-AMINO-4-NITROBENZENE ANIUNE, 4-NITRO- AZOAMINE RED ZH AZOIC DIAZO COMPONENT 37 BENZEN-AMINE, 4-NITRO-(9CI) C.I. 37035 C.I. AZOIC DIAZO COMPONENT 37 C.I. DEVELOPER 17 DEVELOPER P DEVOL RED GG DIAZO FAST RED GG FAST RED BASE GG FAST RED BASE 2J FAST RED 2G BASE FAST RED GG BASE FAST RED MP BASE FAST RED P BASE NAPHTOELAN RED GG BASE NCI-C60786 p-NITRANILINE 4-NITRANILINE NITRAZOL CF EXTRA p-NITROANILINA p-NITROANILINE 4-NITROBENZENAMINE p-NITROPHENYLAMINE PNA RCRA WASTE NUMBER P077 RED 2G BASE SHINNIPPON FAST RED GG BASE... 

Chloro-3- [(1 -ethoxycarbonyl-1 -methylethyl)amino] -4-nitrobenzene (61) gave 6-chloro-3,3-dimethyl-3,4-dihydro-2(l //)-quinoxalinone (62) (TiCl3, AcONa, HeO-MeOH, 20°C, 2.5 h >95%).1042... 

Aminonitrobenzene, see 4-Nitroaniline p-Aminonitrobenzene, see 4-Nitroaniline l-Amino-2-nitrobenzene, see 2-Nitroaniline l-Amino-3-nitrobenzene, see 3-Nitroaniline... 

Methylene bis-( 3,4,6-trichlorophenol) Pentachlorophenol l-n-Propoxy-2-amino-4-nitrobenzene p-Guanylbenzenesulfonamide... 

Several chemical methods have been devised for identifying the N-terminal amino acid. They all take advantage of the fact that the N-terminal amino group is free and can act as a nucleophile. The a-amino groups of aU the other amino acids are part of amide linkages, are not free, and are much less nucleophilic. Sanger s method for N-terminal residue analysis involves treating a peptide with l-fluoro-4-nitrobenzene, which is very reactive toward nucleophilic aromatic substitution. 

When Sanger s method for N-terminal residne analysis was discnssed, yon may have wondered why it was not done sequentially. Simply start at the N terminns and work steadily back to the C terminus identifying one amino acid after another. The idea is fine, bnt it jnst doesn t work well in practice, at least with l-flnoro-4-nitrobenzene. 

Dapsone has been prepared by a number of procedures (1,48). One procedure employs the reaction of l-chloro-4-nitrobenzene with excess sodium sulfide to give the 4-amino-4 -nitrodiphenyl sulfide. This compound, after acetylation of the amino group, is oxidized with H2O2 to the sulfone. The nitro group is then reduced to amino, and hydrolysis of the acetyl gives the product. 

In the past many other synthetic sweet substances were temporarily used as sweeteners, such as 2-amino-l-propoxy-4-nitrobenzene or 6-chlorotryptofan (about 100 times sweeter than sucrose), and so on. They have not found wider application, in particular due to toxicological reasons. 

Arylisoxazol-5(4//)-oncs 21 react with benzene-1,2-diamines to yield 4-aryl-l,5-benzodiaze-pinones 22 by elimination of hydroxylamine from the intermediate oximes. Unsymmetrically substituted benzene-1,2-diamines are attacked at the more nucleophilic amino group. Thus, 4-methylbenzene-1,2-diamine gives 7-methylbenzodiazepinones 22f-h, whereas 4-nitrobenzene-1,2-diamine gives 8-nitro compounds 22k-n. The benzodiazepinones are accompanied by minor amounts of 2-methylbenzimidazoles 23. Selected examples are given.275... 

Compound 9 is prepared by 1 2 chromation in organic medium [12] Diazo-tized l-amino-2-hydroxy-4-nitrobenzene is coupled with 1-phenyl-3-methyl-5-pyrazolone. The resulting azo dye is heated at 110 °C in a mixture of formamide and a aqueous solution of chromium(m) formate. After completion of chromation, the dye 9 [64560-69-6] is precipitated with water. 

In the stepwise synthesis of the unsymmetrical complex dye 13 [ 70236-60-1] [10], the azo dye made from diazotized l-amino-2-hydroxy-5-nitrobenzene and 1-phenyl-3-methyl-5-pyrazolone and the 1 1 chromium complex obtained from 6-nitro-l-diazo-2-hydroxynaphthalene-4-sulfonic acid and 2-naphthol are heated together at 80 °C for 5 h. The adduct is salted out with NaCl. A black powder is obtained that dyes wool and leather in dark brown shades. The resulting colors are fast, particularly on shrink-resistant wool. 

Amino-5-aryl-l,3,4-oxadiazoles form stable N-nitrosamines (71c) which are converted into hydrazines (7ld) with zinc in acetic acid. Treatment of the hydrazine (71d) with nitrous acid yields the corresponding azide and with benzaldehyde a hydrazone is formed (B-61MI42300). On heating in benzene or in nitrobenzene, the nitrosamine (71c) undergoes the Gomberg-Bachmann reaction to yield 2,5-diaryl-l,3,4-oxadiazoles (73JCS(P1)1357). 

SYNS AMARTHOL FAST SCARLET G BASE AMARTHOL FAST SCARLET G SALT l-AMINO-2-METHYI S-NITROBENZENE 2-AMINO-4-NITROTOLUENE AZOENE FAST SCARLET GC BASE... 

Diaza-l-oxathietanes are formed in the reaction of l-amino-l,3-dihydro-2H-indole-2-one with dimethyl sulfoxide in the presence of lead tetraacetate and as intermediates in the reaction of nitrobenzene andjV-sulfinylaniline. °... 

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