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Kofler bank

The filtrate is evaporated under vacuum and the residue is crystallized from a solution of 60 parts of isopropanol in 75 parts of water. There are obtained 9 parts of N-(3-sulfamyl-4-chlorobenzamido)-2-methyl indoline, MP (K) 184° to 186°C, MP (MK) 160° to 162°C (isopropanol/water). [The melting points being determined on a Kofler heater plate under the microscope (MK) or on a Kofler Bank (K)]. ... [Pg.808]

The melting point is the temperature at which the solid and the liquid phases of a substance are in equilibrium. For crystalline substances it represents the most important identification constant and the criterion of purity. For analytical purposes, it is determined predominantly on a microscale by four different methods in a capillary, on the so-called Kofler bank (or Maquenne block), under the microscope, and by various automatic procedures. A correct interpretation of the melting point is dependent on the values... [Pg.36]


See other pages where Kofler bank is mentioned: [Pg.1899]    [Pg.39]    [Pg.1899]    [Pg.39]   
See also in sourсe #XX -- [ Pg.39 ]




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