Kinetic Resolution of Sulfur Compounds

Chiral ferrocenes are of interest in several areas. Their main use is in asymmetric catalysis as chiral hgands of transition-metal complexes employed in a number of various reactions, but they have also been used as modular units in materials science and could be of importance as structural units of products with biological or biochemical activities [316]. In 2003, Uemura et al. [317] reported 

In 2009, the first organocatalytic KR of a planar-chiral ferrocenecarbalde-hyde was reported by the same authors [320]. Therefore, when 2-(2-pyrimidyl)-ferrocenecarbaldehyde was reacted with acetone in dimethylsulfoxide (DMSO) and L-proline as a catalyst, the enantioenriched starting material was obtained with a moderate selectivity factor of 9.2, along with two optically active crotonized products. 

This chapter presents the principal and highly versatile reactions that are based on catalytic non-en2ymatic KR methodologies and illustrates in depth the diversity of useful products that can be obtained through the use of this powerful concept. 

and Miller, S.J. (2004) in Comprehensive Asymmetric Catalysis, Supplement 1 (eds E.N. Jacobsen, A. Pfaltz, and H. Yamamoto), Springer-Verlag, Berlin, pp. 189-206. 

Belmonte, M.M., Escudero-Adan, E.C., Benet-Buchholz, 

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