Kidney disease uremic syndrome

Remuzzi G, Galbusera M, Salvadori M, et al. Bilateral nephrectomy stopped disease progression in plasma-resistant hemolytic uremic syndrome with neurological signs and coma. Kidney Int 49 282-6,1996. 

In general, most strains of E. coli are avirulent however, there are strains that cause an impressive variety of different types of diseases, including diarrhea, dysentery, hemolytic uremic syndrome, bladder and kidney infections, septicemia, pneumonia, and meningitis. A strain of E. coli associated with a particular disease is due to the fact that the organism has acquired a set of virulence genes. 

Diseases of the kidney that are discussed in this section include (1) the uremic syndrome, (2) chronic kidney disease, (3) end-stage renal disease, (4) diabetic nephropathy, (5) hypertensive nephropathy, (6) glomerular diseases, (7) interstitial nephritis, (8) polycystic Iddney disease, (9) polycystic kidney disease, (10) toxic nephropathy, (11) obstructive uropathy, (12) tubular diseases, (13) renal calculi, and (14) cystinuria. In addition, this section also includes discussions on (1) prostaglandins and NS AIDS in kidney disease, (2) monoclonal light chains and kidney disease, and (3) urinary osmolality. 

In the last 15 years, several important diseases of unknown cause have turned out to be complicatioas of foodborne infections. For example, we now know that the Guillain-Barre. syndrome can be caused by Campylobacter infection, and that the most common cause of acute kidney failure in children, hemolytic uremic syndrome, is cau.sed by infection with E. coli 0157 H7 and related bacteria. In the future, other diseases whose origins are currently unknown may turn out be related to foodborne infections. 

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