Ketoprofen Electrodes

Ketoprofen can also be determined using another classic, ion-selective electrode [76] with very similar parameters in between those of the two electrodes described above. The active ingredient of the polymer membrane is a complex of ketoprofen and rhoda-mine 6G. The electrode shows a deviation of (58.0 1.0 mV decade Hn the concentration range of 1.0 x 10 to 1.0 x 10 S detection limit of 6.3 x 10 mol L short response time of 3-4 s and lifetime of approx. 4 months. By using this electrode, ketoptofen was determined with a standard deviation of s 0.21 and s 0.27 in the following preparations Fastum gel (Berlin-Chemie/Menarini) and Ketonal injections (Sandoz). 

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J. Lenik, C. Wardak, B. Marczewska, Ketoprofen ion-selective electrode and its application to phcumaceutical cuialysis, Acta Poloniae Pharmaceutica-Drug Research, 63 (4), 239-244, 2006. 

J. Lenik, Properties of ion-selective electrodes with polymeric membranes for ketoprofen determination. Journal of Analytical Chemistry, 67 (6), 543-549, 2012. 

Z. Kormosh, 1. Hunka, Y. Bazel, O. Matviychuk, Potentiometric determination of ketoprofen and piroxicam at a new PVC electrode based on ion associates of Rhodamine 6G, Materials Science and Engineering C, 30 (7), 997-1002,2010. 

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