Ketones, vide carbonyl compounds derivatives

High molecular weight perfluorinated tertiary alcohols can be prepared by the reaction of (perfluoroalkyl)- and (perfluorooxaalkyl)trimethylsilanes with fluoro ketones (vide supra). The reaction has been extended to carbonyl compounds other than ketones acid fluorides gave ketones, but no reaction was observed with esters. a-Oxo esters react with trimethyl(tri-fluoromcthyl)silane with fluoride initiation in tetrahydrofuran /(./(. -trifluoro lactic acid derivatives are produced in good yields in one step. 

Dithioketals and dithioacetals can be induced to undergo reductive desulfurization on heating alcoholic solutions of those dithio-derivatives in the presence of moist Raney nickel (see, e.g., page 746). These sulfur compounds are prepared by treating the aldehyde or ketone with 1,2-ethanedithiol (CAUTION STENCH) in the presence of an add catalyst (an addition to the carbon of the carbonyl with loss of water, a process that will be discussed at length, vide infra) (Scheme 9.13). 

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